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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTTN All Species: 15.76
Human Site: Y334 Identified Species: 31.52
UniProt: Q14247 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14247 NP_005222.2 550 61586 Y334 V T Q V S S A Y Q K T V P V E
Chimpanzee Pan troglodytes XP_508613 542 59878 M334 T I V E S P A M Q K G F P V A
Rhesus Macaque Macaca mulatta XP_001100193 550 61624 Y334 V T Q V S S A Y Q K T V P V E
Dog Lupus familis XP_851317 541 60553 Y334 V A Q V A P A Y Q K T V P V E
Cat Felis silvestris
Mouse Mus musculus Q60598 546 61241 Y334 V V Q V P S A Y Q K T V P I E
Rat Rattus norvegicus Q9JHL4 436 48594 Q260 Q E W E S A G Q Q A P H P R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507265 462 52591 A286 A E R A Q R M A K E K Q E Q E
Chicken Gallus gallus Q01406 563 63311 Y343 I E K P T S T Y Q K T K P V E
Frog Xenopus laevis Q6GM14 376 42749 E200 E H R R A N V E K D R L E R E
Zebra Danio Brachydanio rerio NP_001004121 504 56595 Q327 A G T F E E V Q K P S A A Y Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU84 531 58711 P330 D A P V P S P P R A A S P A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999782 587 64904 E334 E S R R K A E E E R G R R Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 98.3 90.5 N.A. 92.1 23.8 N.A. 64.9 83.4 26.7 68 N.A. 21.4 N.A. N.A. 46.5
Protein Similarity: 100 91 99 94.1 N.A. 95 40.1 N.A. 74.1 90 41.2 80 N.A. 38 N.A. N.A. 59.8
P-Site Identity: 100 40 100 80 N.A. 80 26.6 N.A. 6.6 53.3 6.6 0 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 40 100 86.6 N.A. 86.6 33.3 N.A. 26.6 73.3 40 20 N.A. 33.3 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 17 0 9 17 17 42 9 0 17 9 9 9 9 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 17 25 0 17 9 9 9 17 9 9 0 0 17 0 67 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 9 0 0 0 0 9 0 0 0 17 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 0 0 9 0 9 0 0 0 25 50 9 9 0 0 9 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 9 17 17 9 9 0 9 9 0 67 0 0 % P
% Gln: 9 0 34 0 9 0 0 17 59 0 0 9 0 17 9 % Q
% Arg: 0 0 25 17 0 9 0 0 9 9 9 9 9 17 0 % R
% Ser: 0 9 0 0 34 42 0 0 0 0 9 9 0 0 0 % S
% Thr: 9 17 9 0 9 0 9 0 0 0 42 0 0 0 0 % T
% Val: 34 9 9 42 0 0 17 0 0 0 0 34 0 42 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 42 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _